Articles Tagged With:
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RSV Vaccination in Severely Immunocompromised Individuals
The antibody response to respiratory syncytial virus vaccination is significantly impaired in many severely immunocompromised individuals.
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Agreeing to Care for Unvaccinated Children
Many primary care clinicians choose not to enroll pediatric patients in their practices when the parents disagree with standard childhood immunization. However, such refusal to provide primary care raises significant controversy and ethical concerns.
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A Plasma Cell-Free DNA PCR Panel Test for Invasive Mold Disease
Lieu and colleagues performed a retrospective study of patients with suspected invasive mold disease that showed a high degree of concordance between noninvasive plasma cell-free deoxyribonucleic acid (DNA) polymerase chain reaction (PCR) testing and invasive specimen fungal test results.
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Clostridioides difficile Toxin Vaccine Failed to Prevent Primary Infection in Trial
A Phase III randomized clinical trial on adults 50 years of age and older found that a detoxified toxin A/B vaccine failed to reach its primary endpoint of preventing Clostridioides difficile infection. The vaccine was safe and well tolerated.
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Uncomplicated Pediatric Appendicitis: Antibiotics or Appendectomy?
Some patients with acute uncomplicated appendicitis do well with initial antibiotic treatment and do not require surgical appendectomy. However, as with adults, approximately one-third of antibiotic-treated children eventually will require surgical removal of the appendix despite the initial short-term success of medical management.
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DeWinter T Waves?
The electrocardiogram (ECG) in the figure was obtained from a woman with dyspnea and marked hypertension, but who had no chest pain. How would you interpret this ECG? Should you activate the cath lab?
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Nemolizumab-Ilto (Nemluvio)
The U.S. Food and Drug Administration has approved nemolizumab, the first monoclonal antibody specifically targeting the interleukin-31 pathway linked to pruritus and skin inflammation associated with atopic dermatitis.
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ABCD2 Score as a Predictor of Three-Year Stroke Risk
This retrospective cohort study using the National Patient Registry in Denmark analyzed a three-year follow-up period following a transient ischemic attack, looking at the rate of recurrent stroke and mortality. The patients were divided into low risk (ABCD2 score 0-3) and high risk (ABCD2 score ≥ 4). The stroke rate was 6% in the high-risk group and 4% in the low-risk group.
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Examining the Effectiveness of Using AI Tools in Practice
A controlled trial comparing physician diagnostic performance with and without artificial intelligence (AI) found no significant difference in accuracy, quality, or other metrics, although AI alone outperformed both groups.
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Prognostic Value of Stress Echocardiography
A UK National Health Service database study of stress echocardiography has shown the degree of ischemia accurately predicts the risk of future cardiovascular events over five years. The same study also showed that a negative test in patients without a history of cardiac disease identifies patients with no more than the expected background risk of an event for patients in this demographic for five years.